Introducing IZERVAY

IZERVAY slows GA, which could help preserve your vision longer

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How IZERVAY worksClinical resultsSide effects

How IZERVAY works

Understanding IZERVAY

Overactive immune system icon

In people with GA, a part of the immune system becomes overactive.

Proteins attacking retinal cell icon

When this happens, immune system proteins in the eye start attacking healthy retinal cells.

Blocking C5 protein icon

Only IZERVAY blocks an immune system protein called C5 to help protect healthy retinal cells for longer.

Feel confident in managing your GA by partnering with your retina specialist to start treatment today

Treat GA early

Clinical results

Protect healthy retinal cells for longer with IZERVAY

IZERVAY is proven to slow GA progression, which could help preserve your vision for longer

IZERVAY significantly slowed GA progression by 18% to 35%, compared to those who were not treated, in 2 clinical trials evaluating 624 people with GA.

SLOWER PROGRESSION IN JUST 1 YEAR OF TREATMENT

Trial 1

(N=177)

Trial 1: IZERVAY slowed GA progression 35%

Trial 2

(N=447)

Trial 2: IZERVAY slowed GA progression 18%

Protection of healthy retinal cells in just 1 year of treatment

Image of Mary, real GA patient


I decided to give IZERVAY a chance because it was hope. I was nervous but I want to preserve my vision for as long as I can, and IZERVAY could help me do that.”– Mary, real GA patient

Quotes reflect patients' experiences at the time of publication.

Side effects

IZERVAY was evaluated in 2 clinical trials

IZERVAY was well-tolerated in 2 clinical trials. The most common side effects include:

Blood in the white of the eye
Blurred vision*
Increase in eye pressure
Wet AMD
Mild corneal irritation
Eye pain

*Blurred vision includes visual impairment and/or loss of sharpness or detail at a distance.

These are not all the possible side effects of IZERVAY. Talk to your doctor if you think you might be experiencing side effects.

Image of Dr. Nicholas Anderson


I've prescribed IZERVAY because of its effectiveness and overall safety profile.”– Dr. Nicholas Anderson

Download the complete brochure to learn more about IZERVAY

English brochure

Physicians featured on IZERVAY.com have been compensated.

See what you can expect from IZERVAY treatment

Getting started

IMPORTANT SAFETY INFORMATION AND USE

Do NOT receive IZERVAY® (avacincaptad pegol intravitreal solution) if you:

  • Have an infection in or around your eye
  • Have active swelling in or around your eye that may include pain and redness

IZERVAY can cause serious side effects including:

  • Eye Infection and Retinal Detachment: Eye injections like the one for IZERVAY can cause an eye infection (endophthalmitis) or separation of layers of the retina (retinal detachment).
  • Wet Age-Related Macular Degeneration (AMD): There is a risk of developing wet age-related macular degeneration (AMD) with IZERVAY. You should report any symptoms (visual distortions such as straight lines seeming bent, deterioration in vision, dark spots, loss of central vision) to your healthcare provider to monitor.
  • Increase in Eye Pressure: IZERVAY may cause a temporary increase in eye pressure after the injection. Your healthcare provider will monitor this after each injection.

Call your healthcare provider right away if you have redness of the eye, eye pain, increased discomfort, worsening eye redness, blurred or decreased vision, an increased number of small specks floating in your vision, flashes of light, or increased sensitivity to light.

Before receiving IZERVAY tell your healthcare provider about all of your medical conditions including if you:

  • Have a history of seeing flashes of light or small specks floating in your vision and if you have a sudden increase of size and number of these specks.
  • Have high pressure in the eye or if you have glaucoma.
  • Are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.
  • Are taking any medications, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tell your healthcare provider about any medicine you take.

What should I avoid while receiving IZERVAY?

  • Your vision may be impaired after receiving an eye injection or after an eye exam. Do not drive or use machinery until your vision has recovered sufficiently.

What are the most common side effects of IZERVAY?

  • Blood in the white of the eye
  • Blurred vision
  • Increase in eye pressure
  • Wet AMD
  • Mild corneal irritation
  • Eye pain

These are not all the possible side effects of IZERVAY. Tell your healthcare provider about any side effect that bothers you or that does not go away.

Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is IZERVAY?

IZERVAY is a prescription eye injection, used to treat geographic atrophy (GA), the advanced form of dry AMD.

Please click here for accompanying full Prescribing Information.

IMPORTANT SAFETY INFORMATION AND USE

Do NOT receive IZERVAY® (avacincaptad pegol intravitreal solution) if you:

  • Have an infection in or around your eye
  • Have active swelling in or around your eye that may include pain and redness

IZERVAY can cause serious side effects including:

  • Eye Infection and Retinal Detachment: Eye injections like the one for IZERVAY can cause an eye infection (endophthalmitis) or separation of layers of the retina (retinal detachment).
  • Wet Age-Related Macular Degeneration (AMD): There is a risk of developing wet age-related macular degeneration (AMD) with IZERVAY. You should report any symptoms (visual distortions such as straight lines seeming bent, deterioration in vision, dark spots, loss of central vision) to your healthcare provider to monitor.
  • Increase in Eye Pressure: IZERVAY may cause a temporary increase in eye pressure after the injection. Your healthcare provider will monitor this after each injection.

Call your healthcare provider right away if you have redness of the eye, eye pain, increased discomfort, worsening eye redness, blurred or decreased vision, an increased number of small specks floating in your vision, flashes of light, or increased sensitivity to light.

Before receiving IZERVAY tell your healthcare provider about all of your medical conditions including if you:

  • Have a history of seeing flashes of light or small specks floating in your vision and if you have a sudden increase of size and number of these specks.
  • Have high pressure in the eye or if you have glaucoma.
  • Are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.
  • Are taking any medications, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tell your healthcare provider about any medicine you take.

What should I avoid while receiving IZERVAY?

  • Your vision may be impaired after receiving an eye injection or after an eye exam. Do not drive or use machinery until your vision has recovered sufficiently.

What are the most common side effects of IZERVAY?

  • Blood in the white of the eye
  • Blurred vision
  • Increase in eye pressure
  • Wet AMD
  • Mild corneal irritation
  • Eye pain

These are not all the possible side effects of IZERVAY. Tell your healthcare provider about any side effect that bothers you or that does not go away.

Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

What is IZERVAY?

IZERVAY is a prescription eye injection, used to treat geographic atrophy (GA), the advanced form of dry AMD.

Please click here for accompanying full Prescribing Information.